I love this question about individual scenes and am going to throw lots of things at you! I'm going to explain the backgrounds to these, forgive me if you already know these shows.

So firstly there's MASH, the show of my heart, which is about a US military hospital near the front lines in the Korean War, staffed by lots of good people who really wish they were somewhere else. They have an episode where a guy has come in claiming that he's Jesus Christ, and won't be convinced otherwise. They find out that he's really a bomber pilot who's had a nervous breakdown, but can't get him to admit to that or anything other than being Jesus. Okay, says Sidney, the unit psychiatrist, if you're Christ, what are you doing here, in this awful place?

Where else would you expect me to be?

All right, says Sidney, who is Jewish. Answer me this. Is it true that God answers all prayers?

And the guy looks up at him, and the camera, and says, "Yes. Sometimes the answer is no."

And this is a show that has only recently taken a turn to being a bit drama as well as comedy and it really is mostly comedy; they've wrung lots of humour out of a guy who thinks he's God. It's a shattering scene, perfectly written and acted, and it kills me every time. Sometimes the answer is no! my god.

Secondly! Deep Space Nine, which is a terribly complicated Star Trek show. Right at the start, it's about these fascist aliens, the Cardassians, who have just withdrawn from Bajor, the planet they've been oppressing with violence for fifty years. One of the main characters, Kira, was a Bajoran Resistance fighter and has spent her entire life fighting, and hating, the Cardassians. Cut to seven years later, when everyone, Bajor, Cardassians and Federation alike, is in a war against the Dominion who want to invade and kill them all. They're already occupying Cardassia, and the guy who takes up the rebellion is a guy named Damar. He's still a Cardassian and was part of the occupying force on Bajor, but he's also an ordinary person with a family, he has a drinking problem but he's trying to quit, etc. He has no idea how to run a rebellion, and Kira the resistance fighter teaches him (with a sigh as to how her life came to this). And they respect each other: Damar values her expertise, and Kira respects a man fighting for his people.

Then the news comes that the Dominion have killed Damar's children back home, and he says, "What kind of people give those orders?"

And Kira turns to him and says, "Yeah, Damar, what kind of people give those orders?"

Damar breaks after that, and it is incredible. Seven years of amazing storytelling has been required to get them to this point, and it puts a crown on it. Finally, someone asks that question. I think about it every time I hear about real-life terrorist movements and occupations. It's just so good.

And finally. Frasier, the sitcom of my heart that isn't MASH, which is about a psychiatrist in Seattle and his extremely neurotic family. Frasier's brother Niles is also a psychiatrist and has just learned that his wife wants a divorce. Which is funny, but played mostly straight; it's really a terrible thing that's happening to him and he's in denial about it. The other plot is a straight-up sitcom plot about Frasier and Niles's father being persuaded to throw away a bunch of crap he got off the shopping channel in the eighties. Then something triggers Niles, and it finally hits him that yes, his wife is leaving him, and his life as he knows it is over, and starts having a panic attack and won't be soothed by his family. He locks himself into the bathroom, and a minute later we hear the sound of a gunshot.

And then he comes out again, covered top-to-toe with shaving foam. Because of an eighties device for heating shaving foam that his father got off the shopping channel. And also much calmer and ready to cope with life. It is so funny, and the characterisation so perfect, I have seen it a thousand times and I laugh every time.

Honestly I love this question! I could probably manage a dozen more.